Iron release analyses from ferritin by visible light irradiation
Iron release analyses from ferritin by visible light irradiation
复制标题
DOI：
10.1080/10715760500177807
复制
发表时间：
2005-08-01
影响因子：
3.3
通讯作者：
Matsugo, S
中科院分区：
文献类型：
--
作者：
Ohishi, K;Zhang, XM;Matsugo, S
我们研究了在ADP存在或不存在的情况下，通过白色荧光灯照射从铁蛋白释放铁。在不存在ADP的情况下以17，000 lx照射铁蛋白溶液轻微诱导铁从铁蛋白释放，但仅在酸性pH条件（pH 5.0或pH 6.0）下。在相同条件下，ADP存在下的辐照显著增强铁蛋白的铁释放。在没有辐射的情况下，铁蛋白的铁释放是低的，即使在ADP的存在下。在ADP存在下通过照射诱导铁释放也受到各种因素的影响，例如照射剂量和酸度，但不受温度（4-47 ° C）、氧浓度或照射期间自由基产生的影响。在照射过程中的铁释放停止增加关闭光，并发现再次增加后，额外的照射。这些结果表明，可见光直接诱导铁释放铁蛋白内储存的铁通过光还原。
We investigated the iron release from ferritin by irradiation from a white fluorescent light in the absence or presence of ADP. Irradiation of a ferritin solution at 17,000 lx in the absence of ADP slightly induces iron release from ferritin but only at acidic pH conditions (pH 5.0 or pH 6.0). Irradiation in the presence of ADP markedly enhances iron release from ferritin under the same conditions. In the absence of irradiation, the iron release from ferritin was low even in the presence of ADP. The induction of the iron release by irradiation in the presence of ADP was also affected by various factors such as irradiation dose and acidity, but not temperature (4-47 degrees C), oxygen concentration, or free radical generations during the irradiation. The iron release during the irradiation ceased to increase by turning off the light and was found to increase again after additional irradiation. These results suggest that visible light directly induces iron release from ferritin via the photoreduction of iron stored inside ferritin.