Traditional uses, phytochemistry, pharmacology and toxicology of Lamiophlomis rotata (Benth.) Kudo: a review.
Traditional uses, phytochemistry, pharmacology and toxicology of Lamiophlomis rotata (Benth.) Kudo: a review.
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Lamiophlomis rotata (Benth.) Kudo 的传统用途、植物化学、药理学和毒理学：综述
作者：
轮纹毒蛾Lamiophlomis roata(Bth.)葛藤是唇形科、唇形亚科的一种草本植物。从轮藻中分离鉴定了127种化学成分，包括环烯醚萜、黄酮类、苯乙醇苷、多糖和有机酸。这些化学成分具有广泛的药理作用，包括抗伤害性、止血、抗炎、抗肿瘤、免疫调节、抗氧化和心脏保护活性。对其在传统医学和现代植物化学和药理学研究中的历史使用的文献表明，轮叶乳杆菌在治疗和保健应用方面具有巨大的潜力。从该植物中分离出的全部提取物和单独的化学成分都显示出广泛的生物活性，值得进一步研究。这些调查可以通过仔细审查来自不同文化背景的现有传统知识而得到协助。寻找新的化学和生物标记，加强对轮叶连翘种质资源的保护，也是确保这一药用资源有针对性和可持续利用的重要因素。本文综述了轮叶连翘的植物学特性、传统用途、民族药理、化学和药理特性、毒性及其保存现状，以期加深对其作用机制的了解，从而开发出新的治疗药物。
Lamiophlomis rotata (Benth.) Kudo is a herbaceous plant of the family Lamiaceae, subfamily Lamioideae. Approximately, 127 chemical constituents have been isolated and identified from L. rotata, including iridoids, flavonoids, phenylethanoid glycosides, polysaccharides, and organic acids. These chemical constituents have extensive pharmacological properties, which include anti-nociceptive, haemostatic, anti-inflammatory, anti-tumour, immunomodulatory, antioxidant, and cardio-protective activities. Documentation of its historical use in traditional medicine and contemporary phytochemical and pharmacological research indicate that L. rotata has significant potential in therapeutic and health care applications. Both whole extracts and individual chemical components isolated from this plant exhibit a wide range of biological activities that warrant further investigation. These investigations can be assisted by careful review of existing traditional knowledge from diverse cultural backgrounds. A new search for chemical and biological markers and reinforced protection of the germplasm resources of L. rotata are also important to ensure targeted and sustainable use of this medicinal resource. The aim of this review was to provide comprehensive information on the botanical characteristics, traditional uses, ethnopharmacology, chemical and pharmacological properties, toxicity profile, and conservation status of L. rotata, to improve understanding of its mechanisms of action so that novel therapeutic agents may be developed from this plant.
影响因子：
1.9
作者：
Dong, S.;Shi, X.;Zhao, L.
通讯作者：
Zhao, L.