Airflow Obstruction and Use of Solid Fuels for Cooking or Heating BOLD (Burden of Obstructive Lung Disease) Results
Airflow Obstruction and Use of Solid Fuels for Cooking or Heating BOLD (Burden of Obstructive Lung Disease) Results
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DOI：
10.1164/rccm.201701-0205oc
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发表时间：
2018-03-01
影响因子：
24.7
通讯作者：
Burney, Peter G. J.
中科院分区：
文献类型：
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作者：
Amaral, Andre F. S.;Patel, Jaymini;Burney, Peter G. J.
基本原理：支持慢性阻塞性肺疾病或气流阻塞与使用固体燃料相关的证据是相互矛盾和不一致的。目的：评估气流阻塞与自我报告的使用固体燃料烹饪或加热的相关性。方法：我们分析了来自BOLD的18，554名成年人，（阻塞性肺疾病负担）研究，提供了可接受的支气管扩张剂后肺功能测定测量值和固体燃料使用信息。使用回归分析，按性别评估了每个地点内气流阻塞与使用固体燃料做饭或取暖的关系。估计值按国民收入分层并进行荟萃分析。我们对肺量限制、慢性咳嗽和慢性痰进行了类似的分析，测量和主要结果：我们发现气流阻塞和使用固体燃料做饭或取暖之间没有关联（优势比[OR] formen，1.20 [95%置信区间（CI），0.94-1.53];女性OR，0.88 [95%CI，0.67-1.15]）。低收入/中等收入和高收入网站都是如此。在从不吸烟者中，也没有证据表明气流阻塞与使用固体燃料有关（男性OR为1.00 [95%CI，0.57-1.76];女性OR为1.00 [95%CI，0.76-1.32]）。总的来说，我们没有发现肺活量限制、慢性咳嗽或慢性痰与使用固体燃料有关。然而，我们发现，慢性痰是更有可能被报道的女性从不吸烟者和那些谁已经暴露了20年或更长的时间。结论：气流阻塞评估后支气管扩张剂肺功能测定与使用固体燃料做饭或取暖。
Rationale: Evidence supporting the association of chronic obstructive pulmonary disease or airflow obstruction with use of solid fuels is conflicting and inconsistent.Objectives: To assess the association of airflow obstruction with self-reported use of solid fuels for cooking or heating.Methods: We analyzed 18,554 adults from the BOLD (Burden of Obstructive Lung Disease) study, who had provided acceptable post-bronchodilator spirometry measurements, and information on use of solid fuels. The association of airflow obstruction with use of solid fuels for cooking or heating was assessed by sex, within each site, using regression analysis. Estimates were stratified by national income and meta-analyzed. We performed similar analyses for spirometric restriction, chronic cough, and chronic phlegm.Measurements and Main Results: We found no association between airflow obstruction and use of solid fuels for cooking or heating (odds ratio [OR] formen, 1.20 [95% confidence interval (CI), 0.94-1.53]; OR for women, 0.88 [95% CI, 0.67-1.15]). This was true for low-/middle- and high-income sites. Among never-smokers, there was also no evidence of an association of airflow obstruction with use of solid fuels (OR for men, 1.00 [95% CI, 0.57-1.76]; ORfor women, 1.00 [95% CI, 0.76-1.32]). Overall, we found no association of spirometric restriction, chronic cough, or chronic phlegm with the use of solid fuels. However, we found that chronic phlegm was more likely to be reported among female never-smokers and those who had been exposed for 20 years or longer.Conclusions: Airflow obstruction assessed from post-bronchodilator spirometry was not associated with use of solid fuels for cooking or heating.