Cytologic diagnosis of small cell anaplastic hepatoblastoma - A case report
Cytologic diagnosis of small cell anaplastic hepatoblastoma - A case report
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DOI：
10.1159/000325933
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发表时间：
2006-03-01
期刊：
影响因子：
1.8
通讯作者：
Rai, S
中科院分区：
文献类型：
--
作者：
Philipose, TR;Naik, R;Rai, S
背景小细胞间变性肝母细胞瘤是肝母细胞瘤中最少见的亚型。文献中很少有文章描述这种罕见亚型的细胞学特征。病例为一名5岁女孩，表现为逐渐增大的腹部肿块。超声检查显示肿块位于肝脏右叶。细针抽吸(FNA)见原始细胞核浆比高，胞核深染、卵圆形，核团粘连较差，散在分布，与单个小圆细胞相似。结论未分化肿瘤的细胞学鉴别诊断。HB必须包括儿童时期的小圆细胞肿瘤。结合临床和放射学资料了解典型的细胞形态特征，可以为FNA提供可靠的术前诊断。
Background Small cell anaplastic hepatoblastoma (HB) is the least common subtype of HB. There are few articles in the literature describing the cytologic characteristics of this rare subtype.Case A 5 year-old girl presented with a progressively enlarging abdominal mass. Ultrasound examination revealed the mass to be arising within the right lobe of the liver. Fine needle aspiration (FNA) of the mass revealed primitive cells with a high nuclear/cytoplasmic ratio and hyperchromatic, ovoid nuclei in poorly cohesive clusters as well as dispersed resembled those of small round cell singly. These cells closely tumors of childhood.Conclusion The cytologic differential diagnosis of undifferentiated. HB must include small round cell tumors of childhood. With knowledge of the typical cytomorphologic appearance in association with clinical and radiologic information, one can offer a reliable preoperative diagnosis on FNA.