Optimal timing for pulmonary valve replacement in adults after tetralogy of Fallot repair

Optimal timing for pulmonary valve replacement in adults after tetralogy of Fallot repair
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DOI:
10.1016/j.amjcard.2004.11.037
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发表时间:
2005-03-15
影响因子:
2.8
通讯作者:
Webb, G
Webb, G
中科院分区:
医学3区
文献类型:
--
作者:
Therrien, J;Provost, Y;Webb, G

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成人法洛四联症修复后肺动脉瓣置换术的时机仍有争议。对17例成人法洛四联症修复患者的磁共振成像研究显示,右心室(RV)容积显著减少(右室舒张末期容积163 +/- 34至107 +/- 26 ml/m2,p < 0.001;肺动脉瓣置换术后平均随访21个月时,右心室收缩末期容积为109 +/- 27至69 +/- 22 ml/m2,p < 0.001);而RV收缩功能保持不变(平均RV射血分数32 ± 7%至34 ± 10%,p = 0.12)。在肺动脉瓣置换术前右心室舒张末期容积> 170 ml/m2或右心室收缩末期容积> 85 ml/m2的患者中,没有一个在手术后右心室容积“正常化”。(c)2005年,Excerpta Medica Inc.
The timing of pulmonary valve replacement in adult patients with repaired tetralogy of Fallot remains controversial. A magnetic resonance imaging study in 17 adult patients with repaired tetralogy of Fallot reveals a statistically significant decrease in right ventricular (RV) volume (RV end-diastolic volume 163 +/- 34 to 107 +/- 26 ml/m(2), p < 0.001; RV end-systolic volume 109 +/- 27 to 69 +/- 22 ml/m(2), p < 0.001) at a mean follow-up of 21 months after pulmonary valve replacement; whereas RV systolic function remained unchanged (mean RV ejection fraction 32 +/- 7 % to 34 10 %, p = 0.12). In no patients with a RV end-diastolic volume > 170 ml/m(2) or a RV end-systolic volume > 85 ml/m(2) before pulmonary valve replacement were RV volumes "normalized" after surgery. (c) 2005 by Excerpta Medica Inc.