Risk factors for prostate cancer: A national case-control study
Risk factors for prostate cancer: A national case-control study
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DOI：
10.1002/ijc.22022
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发表时间：
2006-10-01
影响因子：
6.4
通讯作者：
Skegg, David C. G.
中科院分区：
文献类型：
--
作者：
Cox, Brian;Sneyd, Mary J.;Skegg, David C. G.
在新西兰，法定的癌症通知提供了一个机会来调查前列腺癌的危险因素，在一个大型的全国人口为基础的病例对照研究。我们分析了923例病例和1224例对照的电话访谈数据。为了纳入这项研究，所有的研究对象都必须结婚过一段时间。我们发现，一级亲属中有前列腺癌病史的人患前列腺癌的风险增加（RR为2.6；95% CI为1.9-3.7），仅结过一次婚且在访谈时仍结过婚的男性患前列腺癌的风险随婚姻时间的延长而增加。在550例病例和819例对照的连续亚组中，收集了20岁和访谈前5年的身高和体重数据。20岁时身高低于或等于1.7米的男性患前列腺癌的风险低于同期身高较高的男性。体重或身体质量指数与患前列腺癌的风险之间没有关联。(c) 2006 Wiley-Liss, Inc。
Statutory notification of cancer in New Zealand provided an opportunity to investigate risk factors for prostate cancer in a large national population-based case-control study. We analyzed data obtained from telephone interviews with 923 cases and 1,224 controls. For inclusion in the study, all subjects had to have been married at some time. We found an increased risk of prostate cancer among those with a history of prostate cancer in first degree relatives (RR 2.6; 95% CI, 1.9-3.7) and an increased risk of prostate cancer with length of marriage among men married only once and still married at interview. For a consecutive subgroup of 550 cases and 819 controls, data on height and weight at age 20 and at 5 years before interview were collected. Men less than or equal to 1.7 m in height at age 20 years had a lower risk of prostate cancer than men taller at that age. There was no association between weight or body mass index and risk of prostate cancer. (c) 2006 Wiley-Liss, Inc.