Comparing the Human and Medaka Genomes
Comparing the Human and Medaka Genomes
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DOI：
10.1002/9780470015902.a0021010
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发表时间：
2008-07
期刊：
影响因子：
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通讯作者：
Takashi Sasaki;N. Shimizu
中科院分区：
文献类型：
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作者：
Takashi Sasaki;N. Shimizu
青鳉（Oryzias latipes）是一种小型硬骨鱼，具有丰富的遗传学和基因组学研究资源，是生命科学研究的理想模式动物。比较人类和青鳉的基因组，在核苷酸序列水平上的基因组，重复元件，基因调控元件和进化保守元件提供了新的信息。基因组信息暗示了脊椎动物谱系中的染色体进化以及青鳉在医学上的应用。关键词：人类;青鳉;基因组;基因;重复元件;进化
Medaka (Oryzias latipes) is a small teleost fish for which well-established resources for genetic and genomic studies are available, hence, medaka has become an excellent laboratory model animal for life sciences. Comparing the human and medaka genomes provided novel information on the sets of genes, repetitive elements, gene regulatory elements and the evolutionary conserved elements at the nucleotide sequence level. The genomic information implied chromosomal evolution in the vertebrate lineage and the use of medaka for medical science. Keywords: human; medaka; genome; genes; repetitive elements; evolution