Evaluation of Commercially Available Serologic Diagnostic Tests for Chikungunya Virus

Evaluation of Commercially Available Serologic Diagnostic Tests for Chikungunya Virus
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DOI:
10.3201/eid2012.141269
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发表时间:
2014-12-01
影响因子:
11.8
通讯作者:
Leparc-Goffart, Isabelle
Leparc-Goffart, Isabelle
中科院分区:
医学2区
文献类型:
--
作者:
Prat, Christine M.;Flusin, Olivier;Leparc-Goffart, Isabelle

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基孔肯雅病毒(CHIKV)存在于或出现在登革热病毒流行地区。由这些病毒引起的感染有一些共同的体征/症状,但预后,患者护理和持续症状不同。因此,准确的诊断方法对于区分感染至关重要。我们评估了4种CHIKV血清学诊断试验,其中2种的敏感性和特异性较差。
Chikungunya virus (CHIKV) is present or emerging in dengue virus endemic areas. Infections caused by these viruses share some common signs/symptoms, but prognosis, patient care, and persistent symptoms differ. Thus, accurate diagnostic methods are essential for differentiating the infections. We evaluated 4 CHIKV serologic diagnostic tests, 2 of which showed poor sensitivity and specificity.