Life expectancy in bipolar disorder
Life expectancy in bipolar disorder
复制标题
DOI：
10.1111/bdi.12296
复制
发表时间：
2015-08-01
影响因子：
5.4
通讯作者：
Andersen, Per Kragh
中科院分区：
文献类型：
--
作者：
Kessing, Lars Vedel;Vradi, Eleni;Andersen, Per Kragh
目的据报道双相情感障碍患者的预期寿命缩短 11 至 20 年。这些计算基于 15 岁个人的数据。然而，这可能会对一般双相情感障碍患者产生误导，因为大多数患者发病较晚。本研究的目的是计算不同年龄的双相情感障碍患者的剩余预期寿命。方法使用 1970 年至 2012 年丹麦所有精神病医院的所有住院和门诊接触者的全国登记册，我们计算了 2000 年所有活着的个体中 15、25、35、75 岁的剩余预期寿命。结果对于 25 至 25 岁的典型男性或女性患者 45岁，剩余预期寿命分别减少12.0-8.7岁和10.6-8.3岁。双相情感障碍患者的剩余预期寿命与普通人群的剩余预期寿命之比随着年龄的增长而下降，表明双相情感障碍患者在成年早期和中期就开始缩短生命年。结论双相情感障碍患者的预期寿命大幅下降，但比之前报道的要少。患者在成年早期和中期开始失去生命年。
ObjectiveLife expectancy in patients with bipolar disorder has been reported to be decreased by 11 to 20years. These calculations are based on data for individuals at the age of 15years. However, this may be misleading for patients with bipolar disorder in general as most patients have a later onset of illness. The aim of the present study was to calculate the remaining life expectancy for patients of different ages with a diagnosis of bipolar disorder.MethodsUsing nationwide registers of all inpatient and outpatient contacts to all psychiatric hospitals in Denmark from 1970 to 2012 we calculated remaining life expectancies for values of age 15, 25, 35 75 years among all individuals alive in year 2000.ResultsFor the typical male or female patient aged 25 to 45years, the remaining life expectancy was decreased by 12.0-8.7years and 10.6-8.3years, respectively. The ratio between remaining life expectancy in bipolar disorder and that of the general population decreased with age, indicating that patients with bipolar disorder start losing life-years during early and mid-adulthood.ConclusionsLife expectancy in bipolar disorder is decreased substantially, but less so than previously reported. Patients start losing life-years during early and mid-adulthood.