Non‐quantitative morphologic features in normal and glaucomatous optic discs
Non‐quantitative morphologic features in normal and glaucomatous optic discs
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正常和青光眼视盘的非定量形态特征
DOI：
10.1111/j.1755-3768.1989.tb01615.x
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发表时间：
1989
影响因子：
3.4
通讯作者：
G. Naumann
中科院分区：
文献类型：
--
作者：
J. Jonas;N. Nguyen;G. Naumann
抽象的。青光眼与视盘地形图的改变有关。使用彩色立体照片，我们检查了308例慢性原发性开角型青光眼患者的584个视盘和236例年龄和屈光度匹配的正常受试者的383个视盘的非定量体征。每例患者和正常受试者仅选择一只眼睛进行统计分析。对正常眼和青光眼的鉴别诊断有最高预测价值的参数是视乳头视网膜神经纤维层的改变。（86.7%），“大小异常”（79.8%）和异常部位（68.6%）的视乳头旁脉络膜视网膜萎缩“，”颞水平盘扇区外的最小神经视网膜边缘部分“（78.5%）和“杯突面积大于苍白面积”（68.2%）。具有高特异性和低敏感性的特征是“视盘出血”，“裸露的睫状视网膜动脉”和“裸露的环行血管”。由于其评价独立于复杂的技术，非定量参数有助于青光眼视神经损伤的特殊诊断。
Abstract. Glaucoma is associated with changes of the optic disc topography. Using color stereo photographs we examined non‐quantitative signs in 584 optic discs of 308 patients with chronic primary open‐angle glaucoma and in 383 optic discs of 236 age and refraction matched normal subjects. Only one eye per patient and normal subject was chosen for statistical analysis. Highest predictive value to differentiate between normal and glaucoma eyes had the parameters ‘changes in the juxtapapillary retinal nerve fiber layer’ (86.7%), ‘abnormal size (79.8%) and abnormal location (68.6%) of the parapapillary chorio‐retinal atrophy’, ‘smallest neuroretinal rim part outside of the temporal horizontal disc sector’ (78.5%), and ‘area with cupping larger than area with pallor’ (68.2%). Characteristics with high specificity and low sensitivity were ‘optic disc haemorrhages’, ‘bared cilioretinal arteries’, and ‘bared circumlinear vessels’. With their evaluation being independent of sophisticated techniques the non‐quantitative parameters are helpful for the ad hoc diagnosis of glaucomatous optic nerve damage.