Dextran based sensitive theranostic nanoparticles for near-infrared imaging and photothermal therapy in vitro
Dextran based sensitive theranostic nanoparticles for near-infrared imaging and photothermal therapy in vitro
复制标题
基于右旋糖酐的敏感治疗诊断纳米粒子，用于体外近红外成像和光热治疗
DOI：
10.1039/c3cc43633k
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发表时间：
2013-01-01
影响因子：
4.9
通讯作者：
Cai, Lintao
中科院分区：
文献类型：
--
作者：
Liu, Peng;Yue, Caixia;Cai, Lintao
通过与葡聚糖嵌段共聚物（peg -葡聚糖（-SS-NH2））的静电相互作用，制备了吲哚菁绿（ICG）纳米粒子作为近红外（NIR）治疗纳米粒子。在细胞内环境下，纳米颗粒可以被近红外荧光从“OFF”激活到“ON”，用于近红外成像和光热治疗。
Indocyanine green (ICG) nanoparticles were developed via electrostatic interactions of ICG and dextran based block copolymers (PEG-dextran(-SS-NH2)) as near-infrared (NIR) theranostic nanoparticles. The nanoparticles could be activated from "OFF'' to "ON'' of NIR fluorescence in an intracellular environment and used for NIR imaging and photothermal therapy.