In vivo response of strontium and zinc-based ionomeric cement implants in bone
In vivo response of strontium and zinc-based ionomeric cement implants in bone
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DOI：
10.1023/a:1014336517741
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发表时间：
2002-04-01
影响因子：
3.7
通讯作者：
Brook, IM
中科院分区：
文献类型：
--
作者：
Johal, KK;Mendoza-Suárez, G;Brook, IM
本研究比较了LG 125和LG 119锶基离子水门汀和LG 130和LG 132锌基离子水门汀的骨传导性能。将湿ICs植入断奶Wistar大鼠股骨内，连续4周。为了评估骨结合的百分比，使用指示器(骨/种植体界面接触的长度)测量种植体的周长和与种植体接触的骨周长。每根离子棒周长随机抽取6个点，测量新生骨厚度，以确定骨传导。以骨传导程度作为种植体表面新生骨的平均厚度。结果表明，锶IC种植体LG125的骨传导能力最强。从这些研究中可以得出结论，组合物LG125可能作为骨水泥提供有用的用途。(C)2002年克鲁沃学术出版社。
In this study the osteoconductive properties of strontium based ionomeric cements (ICs) named, LG 125 and LG 119, as well as zinc-based ICs, designated by LG 130 and LG 132, were compared. Wet ICs were surgically implanted into the femora of weaned Wistar rats for 4 weeks. To assess the percentage osseointegration the perimeter of the implant and the perimeter of bone in contact with the implant were measured using a pointer (the length of bone/implant interfacial contact). Osteoconduction was determined by taking six points at random around the perimeter of each ionomeric rod measuring the thickness of newly formed bone. The degree of osteoconduction was taken as the average thickness of new bone produced on the implant surface. It was found that osteoconduction was greatest in the strontium based IC implant LG125. From these studies it can be concluded that the composition LG125 might provide a useful purpose as a bone cement. (C) 2002 Kluwer Academic Publishers.