The application accuracy of a skull-mounted trajectory guide system for image-guided functional neurosurgery.
The application accuracy of a skull-mounted trajectory guide system for image-guided functional neurosurgery.
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DOI：
10.3109/10929080500050249
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发表时间：
2004-01-01
期刊：
影响因子：
--
通讯作者：
Rosenow, Joshua M
中科院分区：
文献类型：
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作者：
Henderson, Jaimie M;Holloway, Kathryn L;Rosenow, Joshua M
目的：传统上，无框架图像引导系统被认为不如立体定向框架准确，限制了它们在基于自动化的程序中的采用，例如需要亚毫米级精度的脑深部刺激器放置。然而，一些研究表明，光学定位系统可以达到很高的精度。我们评估了应用的准确性，头骨安装的轨迹引导耦合到一个光学图像引导手术systemintheLaboratorySetting.MATERIALS和METHODS：一个塑料头骨幻影装有5个基准标记，通过自钻骨螺钉刚性连接。在25个不同的中心获得了不同的MRI和CT成像方案。将以1 mm增量标记的金属圆盘放置在预期靶点处。轨迹导向器配准和对齐后，测量径向和深度定位误差。结果：平均定位误差为1.25 mm，95%可信区间为2.7 mm，99.9%可信区间为4.0 mm，均显著低于两种最常用的支架系统（P <0.01）。
OBJECTIVE: Frameless image guided systems have traditionally been perceived as being less accurate than stereotactic frames, limiting their adoption for trajectory-based procedures such as deep brain stimulator placement which require submillimetric accuracy. However, some studies have suggested that high degrees of accuracy are attainable with optical localization systems. We evaluated the application accuracy of a skull-mounted trajectory guide coupled to an optical image-guided surgery system in a laboratory setting.MATERIALS AND METHODS: A plastic skull phantom was fitted with five fiducial markers rigidly attached via self-drilling bone screws. Varying MRI and CT imaging protocols were obtained at 25 different centers. A metal disc marked in 1-mm increments was placed at the expected target point. Following registration and alignment of the trajectory guide, radial and depth localization errors were measured. A total of 560 measurements were obtained and detailed statistical analyses were performed.RESULTS: Mean localization error was 1.25 mm with a 95% confidence interval of 2.7 mm and a 99.9% confidence interval of 4.0 mm. These values were significantly lower than those published for the two most widely used frame systems (p