5-Alkylpyrrole-2-carboxaldehydes from the Caribbean sponges Mycale microsigmatosa and Desmapsamma anchorata

5-Alkylpyrrole-2-carboxaldehydes from the Caribbean sponges Mycale microsigmatosa and Desmapsamma anchorata
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DOI:
10.1080/10575639908048787
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发表时间:
1999-01-01
期刊:
NATURAL PRODUCT LETTERS
影响因子:
--
通讯作者:
Gómez, M
Gómez, M
中科院分区:
其他
文献类型:
--
作者:
Compagnone, RS;Oliveri, MC;Gómez, M

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从海绵 Mycale microsigmatosa 和 Desmapsamma anorata 中分离出 13 种新的 5-烷基吡咯-2-甲醛 1、3、5、6、7、8、9、10、11、12、13、14 和 15。通过分析光谱数据来确定它们的结构。腈1对墨西哥利什曼原虫表现出中等活性。
Thirteen new 5-alkylpyrrole-2-carboxaldehydes 1, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14 and 15 were isolated from the sponges Mycale microsigmatosa and Desmapsamma anchorata. Their structures were assigned by analysis of the spectroscopic data. The nitrile 1 showed moderate activity against Leishmania mexicana.