Communication distance in the intercellular signaling by cyto/chemokine or autacoid
Communication distance in the intercellular signaling by cyto/chemokine or autacoid
复制标题
细胞/趋化因子或自体信号在细胞间信号传导中的通讯距离
DOI：
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发表时间：
1999
期刊：
影响因子：
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通讯作者：
K. Horiike
中科院分区：
文献类型：
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作者：
F. Yoshida;K. Horiike
通过单细胞模型研究了细胞间运输中信号传递过程的特性。在给定细胞表面通量的边界条件下，求解了球形细胞分泌分子的扩散方程。Francis和Palsson将该溶液与细胞表面恒定源对应的另一种溶液进行了物理化学比较。1)讨论了人类细胞因子估计的通信距离（-50μm）。
Characteristic properties of signaling processes are studied by a single cell model in the intercellular transport. The diffusion equation is solved for molecules secreted from a spherical cell under the boundary conditions of prescribed fluxes at the cell surface. The solution is physicochemically compared with another one corresponding to constant source at the cell surface by Francis and Palsson. 1) Discussion is given on communication distances (-50μm) estimated for human cytokines.