Central injections of noradrenaline induce reinstatement of cocaine seeking and increase c-fos mRNA expression in the extended amygdala
Central injections of noradrenaline induce reinstatement of cocaine seeking and increase c-fos mRNA expression in the extended amygdala
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DOI：
10.1016/j.bbr.2010.09.025
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发表时间：
2011-03-01
影响因子：
2.7
通讯作者：
Erb, Suzanne
中科院分区：
文献类型：
--
作者：
Brown, Zenya J.;Nobrega, Jose N.;Erb, Suzanne
我们最近报道了中枢注射去甲肾上腺素（NA）诱导大鼠可卡因觅药的恢复。在这里，我们复制和扩展我们的发现，以额外的剂量NA和显示，它是与诱导c-fos mRNA表达（神经元激活的标志物）在功能相关的大脑区域，包括床核的终纹和中央核杏仁核。(C)2010爱思唯尔有限公司版权所有。
We recently reported that central injections of noradrenaline (NA) induce reinstatement of cocaine seeking in rats. Here, we replicate and extend our finding to an additional dose of NA and show that it is associated with the induction of c-fos mRNA expression (a marker of neuronal activation) in functionally relevant brain regions, including the bed nucleus of the stria terminalis and central nucleus of the amygdala. (C) 2010 Elsevier B.V. All rights reserved.