Applications of Sharp less asymmetric epoxidation in total synthesis
Applications of Sharp less asymmetric epoxidation in total synthesis
复制标题
DOI：
10.1016/j.tetasy.2015.03.006
复制
发表时间：
2015-04-30
影响因子：
--
通讯作者：
Poorahmad, Nasim
中科院分区：
文献类型：
--
作者：
Heravi, Majid M.;Lashaki, Tahmineh Baie;Poorahmad, Nasim
本文介绍了前手性烯丙醇的不对称环氧化反应，即“Sharpless不对称环氧化反应”，即“动力学拆分”的应用。该反应导致相应的2，3-环氧醇以高立体选择性作为用于合成复杂目标物（例如天然存在的生物活性分子）的优异起始材料。(C)2015爱思唯尔有限公司版权所有。
This report presents the applications of enantioselective epoxidation of prochiral allylic alcohols, so called 'Sharpless asymmetric epoxidation', which is frequently referred as 'kinetic resolution'. This reaction results in the corresponding 2,3-epoxy alcohols in high stereoselectivity as excellent starting materials for the synthesis of complex targets, such as naturally occurring biologically active molecules. (C) 2015 Elsevier Ltd. All rights reserved.