INFANTILE EXPERIENCE WITH SUCKLING ODORS DETERMINES ADULT SEXUAL-BEHAVIOR IN MALE-RATS
INFANTILE EXPERIENCE WITH SUCKLING ODORS DETERMINES ADULT SEXUAL-BEHAVIOR IN MALE-RATS
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DOI：
10.1126/science.3945807
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发表时间：
1986-02-14
期刊：
影响因子：
56.9
通讯作者：
BLASS, EM
中科院分区：
文献类型：
--
作者：
FILLION, TJ;BLASS, EM
由于幼年大鼠了解引起哺乳的气味，并且由于有助于成年交配行为的某些化学感应线索与引起哺乳的化学感应线索相似，因此进行了一项实验来评估婴儿期经历的与哺乳相关的气味对成年性行为的影响。幼鼠与母鼠一起生活并哺乳，母鼠的乳头和阴道气味被柠檬醛（一种柠檬气味）改变。这些大鼠断奶后，在测试之前不再暴露于柠檬醛或雌性大鼠。在大约 100 天大时，雄性在交配测试中与正常的性接受性雌性或在测试前立即在阴道周围用柠檬醛处理过的性接受性雌性配对。当与经过柠檬醛处理的雌性配对时，雄性很容易射精，但与正常雌性配对时，射精速度很慢。这些发现表明婴儿时期的经历是哺乳动物成年性行为的决定因素。
Because infant rats learn about odors that elicit suckling, and because certain chemosensory cues that help mating behavior in adults are similar to those that elicit suckling, an experiment was undertaken to assess the influence of suckling-associated odors experienced during infancy on adult sexual behavior. Rat pups lived with and suckled dams whose nipple and vaginal odors were altered with citral, a lemon scent. The rats were weaned and never exposed again, until testing, to citral or females. At about 100 days of age, the males were paired in mating tests with a normal sexually receptive female or with a sexually receptive female that had been treated perivaginally with citral immediately before testing. The males ejaculated readily when paired with citral-treated females but were slow to achieve ejaculation when paired with normal females. These findings implicate an infantile experience as a determinant of adult sexual behavior in a mammal.