Sample size considerations in human muscle architecture studies.

Sample size considerations in human muscle architecture studies.
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DOI:
10.1002/mus.23283
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发表时间:
2012-05
期刊:
影响因子:
3.4
通讯作者:
Lieber, Richard L.
Lieber, Richard L.
中科院分区:
医学3区
文献类型:
--
作者:
Tuttle, Lori J.;Ward, Samuel R.;Lieber, Richard L.

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本报告是对人体肌肉结构文献的荟萃分析,分析了肌肉数量、受试者数量和肌肉纤维长度变异系数(CV)的身体区域。肌纤维长度数据用于建议基于解剖的建筑研究样本大小。在所考虑的26项研究中,平均报告了9±10 (mean±SD)块肌肉和9±5个受试者。在所有研究中,平均纤维长度CV变化很大(18%±5%)。这表明获得足够功率所需的样本量因解剖区域而异。涉及肌肉结构的研究应考虑区域差异和效应大小,并相应地确定样本量。
This report is a meta-analysis of the human muscle architecture literature that analyzes the number of muscles, number of subjects, and muscle fiber length coefficient of variation (CV) by body region. Muscle fiber length data are used to make recommendations for dissection-based architectural study sample sizes. An average of 9 ± 10 (mean ± SD) muscles and an average of 9 ± 5 subjects were reported in the 26 studies considered. Across all studies, average fiber length CV was highly variable (18% ± 5%). This shows that sample sizes required to achieve adequate power varies by anatomical region. Studies involving muscle architecture should consider regional variability and effect size and determine sample size accordingly.
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