ADULT RESPIRATORY-DISTRESS SYNDROME - RISK WITH COMMON PREDISPOSITIONS
ADULT RESPIRATORY-DISTRESS SYNDROME - RISK WITH COMMON PREDISPOSITIONS
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DOI：
10.7326/0003-4819-98-5-593
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发表时间：
1983-01-01
影响因子：
39.2
通讯作者：
HYERS, TM
中科院分区：
文献类型：
--
作者：
FOWLER, AA;HAMMAN, RF;HYERS, TM
对3家医院的患者进行了为期1年的调查，确定了936例有1种成人呼吸窘迫综合征易感性的患者和57例有多种成人呼吸窘迫综合征易感性的患者。在993例患者的总易感人群中，68例随后发展为综合征。另有20名患者因8种确定的易感性以外的原因而患上该综合征，使研究的患者总数达到88例。有1种和多种易感性的患者的综合征发生率（5.8比24.6/100例患者）有非常显著的差异（P < 0.0001）。在易感性发作后72小时内，89.5%发生综合征的患者接受了插管和机械通气。88例中死亡57例（64.8%）。到第14天，90%的人死亡。在发病率或死亡率方面没有年龄或性别特异性差异。在所有易感人群中，该综合征的病死率都很高。
A 1-yr survey of patients in 3 hospitals identified 936 patients who had 1 predisposition and 57 who had several predispositions to adult respiratory distress syndrome. From the total predisposed population of 993 patients, 68 subsequently developed the syndrome. An additional 20 patients developed the syndrome from causes other than 8 identified predispositions, to bring the total of patients studied to 88. A highly significant difference (P < 0.0001) was found in the incidence rates of the syndrome between patients with 1 and several predispositions (5.8 vs. 24.6/100 patients). Within 72 h of onset of predisposition, 89.5% of patients who developed the syndrome had been intubated and placed on mechanical ventilation. Of the 88 patients with the syndrome 57 (64.8%) died. By the 14th day 90% of deaths had occurred. There were no age- or sex-specific differences in either incidence or mortality rates. Case fatality rates of the syndrome were high in all predisposed groups.