Controversy: neonatal exposure to plasticizers in the NICU.
Controversy: neonatal exposure to plasticizers in the NICU.
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争议：新生儿重症监护室中的新生儿接触塑化剂。
DOI：
10.1097/01.nmc.0000281965.45905.c0
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发表时间：
2007
期刊：
影响因子：
--
通讯作者：
McCauley,LindaA
中科院分区：
文献类型：
--
作者：
Pak,VictoriaM;Nailon,ReginaE;McCauley,LindaA
本文对现有文献进行了综述，介绍了我们目前对邻苯二甲酸二（2-乙基己基）酯（DEHP）暴露对新生儿影响的理解。邻苯二甲酸酯（如DEHP）增加了塑料的柔韧性。DEHP是医疗环境中常用的聚氯乙烯器械生产的主要成分。NICU中的早产儿和危重新生儿和婴儿暴露于DEHP，因此可能会增加不良健康结局的风险。DEHP已被证明是一种发育和内分泌干扰毒物，是聚氯乙烯塑料的主要成分，通常在NICU使用的医疗设备中发现。对NICU中婴儿的潜在毒性是一个问题，因为婴儿的体型小和身体状况受损需要多种医疗干预，每种干预都会增加暴露水平。扩大护士关于DEHP研究的知识对于实施预防方法以减少NICU患者的DEHP暴露非常重要。
This article presents a review of extant literature that informs our current understanding of the effects of di-(2-ethylhexyl) phthalate (DEHP) exposure on neonates. Phthalates such as DEHP add flexibility to plastics. DEHP is a major component in the manufacturing of polyvinyl chloride devices commonly used in the healthcare setting. Premature and critically ill neonates and infants in the NICU are exposed to DEHP and may be at an increased risk for adverse health outcomes as a result. DEHP has been shown to be a developmental and endocrine disrupting toxicant and is a major component in polyvinyl chloride plastics, which are commonly found in medical equipment used in the NICU. Potential toxicities to infants in the NICU are a concern because infants’ small body size and compromised physical condition necessitate a multitude of medical interventions, each increasing exposure levels. Expanding nurses’ knowledge regarding DEHP research is important for implementing a precautionary approach to reduce DEHP exposure among NICU patients.