Misalignments in the Retinal Nerve Fiber Layer Evaluation Using Cirrus High-definition Optical Coherence Tomography
Misalignments in the Retinal Nerve Fiber Layer Evaluation Using Cirrus High-definition Optical Coherence Tomography
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DOI：
10.1097/ijg.0b013e3181fa0def
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发表时间：
2011-12-01
影响因子：
2
通讯作者：
Gomez-Munoz, Alicia
中科院分区：
文献类型：
--
作者：
Moreno-Montanes, Javier;Anton, Alfonso;Gomez-Munoz, Alicia
目的：目的：探讨视网膜神经纤维层（retinal nerve fiber layer，RNFL）谱域光学相干断层扫描（spectral-domain opticalcoherence tomography，Cirrus）分析中错位（misalignments，MAs）的发生频率和特征，并分析影响MAs发生的相关因素。当MA仅影响扫描线的一部分时，MA被认为是有限的，当在整个扫描线中观察到MA时，MA被认为是完整的（CMA）。结果：140眼（46.7%）发现局限性MAs 299个，其中91眼（30.3%）发现局限性MAs 151个。CMA的发生频率和数量与年龄显著相关（P < 0.05）。在48只眼中，72个CMA位于测量环内，在3点和9点位置（P = 0.001）和水平象限（P = 0.001）更常见。在重复扫描中，CMA的病例数与首次扫描相似（P = 0.32）。没有显着差异，发现在全球或象限RNFL厚度扫描与无CMAs.Conclusions：CMA存在于第一次或第二次扫描中约30%的情况下，与年龄较大。CMA多见于水平经线和象限。在相同的患者中，在有和没有CMA的扫描之间没有发现RNFL厚度的差异。在RNFL评估中可以考虑在测量环中使用CMA进行扫描。
Purpose: To evaluate the frequency and characteristics of misalignments (MAs) in the retinal nerve fiber layer (RNFL) analysis protocol of spectral-domain optical coherence tomography (Cirrus) and determine factors associated with MAs.Methods: Three hundred eyes (162 normal and 138 glaucomatous eyes) were included in this cross-sectional study. The MAs were considered limited when they affected only part of the scan line, and complete (CMA) when they were observed in the entire scan line. A subgroup (153 cases) with repeated scans was analyzed to compare the RNFL thicknesses in the scans with and without CMAs.Results: Two hundred ninety-nine limited MAs were found in 140 eyes (46.7%) and 151 CMAs were found in 91 eyes (30.3%). The frequency and number of CMAs were significantly related to age (P < 0.05). Seventy-two CMAs were in the measurement ring in 48 eyes, more frequently in the 3 and 9-o'clock positions (P = 0.001) and the horizontal quadrants (P = 0.001). Among the repeated scans, the number of cases with CMAs was similar to the first scan (P = 0.32). No significant differences were found in global or quadrant RNFL thickness between scans with and without CMAs.Conclusions: CMAs were present in the first or second scans in about 30% of cases and were related to older age. CMAs were more frequently in horizontal meridians and quadrants. No differences in RNFL thickness were found between scans with and without CMAs in the same patients. Scans with CMAs in the measurement ring can be considered in the RNFL evaluation.