From Metal Binding to Nanoparticle Formation: Monitoring Biomimetic Iron Oxide Synthesis within Protein Cages using Mass Spectrometry
From Metal Binding to Nanoparticle Formation: Monitoring Biomimetic Iron Oxide Synthesis within Protein Cages using Mass Spectrometry
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DOI：
10.1002/anie.200900437
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发表时间：
2009-01-01
影响因子：
16.6
通讯作者：
Douglas, Trevor
中科院分区：
文献类型：
--
作者：
Kang, Sebyung;Jolley, Craig C.;Douglas, Trevor
金属矿化蛋白笼的质量测量可以定量检测金属离子浓度对最终纳米颗粒大小的影响。使用动力学主方程建模表明，颗粒生长包括结合阶段和生长阶段（见图；I：相对丰度；LiDps: DNA结合蛋白；nFe：铁原子数）。
Mass measurementsof metal‐mineralized protein cages allowed quantitative examination of the effects of metal‐ion concentration on the final nanoparticle size. Modeling using a kinetic master equation suggests that particle growth involves both a binding phase and a growth phase (see picture;I: relative abundance; LiDps: a DNA binding protein;nFe: number of Fe atoms).