Haploview: analysis and visualization of LD and haplotype maps

Haploview: analysis and visualization of LD and haplotype maps
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DOI:
10.1093/bioinformatics/bth457
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发表时间:
2005-01-15
期刊:
影响因子:
5.8
通讯作者:
Daly, MJ
Daly, MJ
中科院分区:
生物学3区
文献类型:
--
作者:
Barrett, JC;Fry, B;Daly, MJ

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过去几年的研究揭示了人类基因组中重要的单倍型结构。这些模式的特征,特别是在医学遗传关联研究的背景下,正在成为一项常规的研究活动。Haploview是一个软件包,它提供了从主要基因型数据中计算连锁不平衡统计和种群单倍型模式的视觉吸引力和交互界面。
Research over the last few years has revealed significant haplotype structure in the human genome. The characterization of these patterns, particularly in the context of medical genetic association studies, is becoming a routine research activity. Haploview is a software package that provides computation of linkage disequilibrium statistics and population haplotype patterns from primary genotype data in a visually appealing and interactive interface.