House dust mite allergen in US beds: Results from the first National Survey of Lead and Allergens in Housing
House dust mite allergen in US beds: Results from the first National Survey of Lead and Allergens in Housing
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DOI：
10.1067/mai.2003.16
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发表时间：
2003-02-01
影响因子：
14.2
通讯作者：
Zeldin, DC
中科院分区：
文献类型：
--
作者：
Arbes, SJ;Cohn, RD;Zeldin, DC
工作背景：虽然暴露于屋尘螨变应原是过敏性致敏和哮喘的主要危险因素，但美国家庭中尘螨变应原水平的全国性估计尚未报道。目的：本研究的目的是估计美国家庭床中尘螨变应原的患病率，并确定尘螨变应原浓度的预测因子。数据来自第一次全国住房铅和过敏原调查，这是一项对831个允许儿童居住的永久居住的非机构住房单元的横断面调查。尘螨过敏原浓度（Der f 1加Der p 1）测定从床上收集的灰尘样品。家庭的百分比与浓度或大于检测，2.0杯/克床尘，10.0杯/克床尘进行了估计。过敏原浓度的独立预测因素进行了评估与多变量线性regression.Results：尘螨过敏原浓度在或大于检测，2.0 μ g/g，和10.0 μ g/g的美国家庭的百分比分别为84.2%（SE，1.73），46.2%（SE，2.0），和24.2%（SE，2.1），分别。较高水平的独立预测因素是老房子，非西部人口普查地区，单户住宅，没有居民儿童，家庭收入较低，加热源以外的其他强制空气，发霉或发霉的气味，以及较高的卧室湿度。以前与过敏性致敏和哮喘相关的水平在美国卧室很常见。预测器可用于确定房屋更有可能增加尘螨过敏原水平的条件。
Background: Although exposure to house dust mite allergen is a major risk factor for allergic sensitization and asthma, nationwide estimates of dust mite allergen levels in US homes have not been reported.Objective: The purpose of this study was to estimate the prevalence of dust mite allergen in beds of US homes and to identify predictors of dust mite allergen concentration.Methods: Data were obtained from the first National Survey of Lead and Allergens in Housing, a cross-sectional survey of 831 permanently occupied noninstitutional housing units that permitted resident children. Dust mite allergen concentration (Der f 1 plus Der p 1) was determined from a dust sample collected from a bed. The percentages of homes with concentrations at or greater than detection, 2.0 mug/g bed dust, and 10.0 mug/g bed dust were estimated. Independent predictors of allergen concentration were assessed with multivariable linear regression.Results: The percentages of US homes with dust mite allergen concentrations at or greater than detection, 2.0 mug/g, and 10.0 mug/g were 84.2% (SE, 1.73), 46.2% (SE, 2.0), and 24.2% (SE, 2.1), respectively. Independent predictors of higher levels were older homes, non-West census regions, single-family homes, no resident children, lower household income, heating sources other than forced air, musty or mildew odor, and higher bedroom humidity.Conclusion: Most US homes have detectable levels of dust mite allergen in a bed. Levels previously associated with allergic sensitization and asthma are common in US bedrooms. Predictors can be used to identify conditions under which homes are more likely to have increased dust mite allergen levels.