REARRANGEMENTS OF THE TRANSPOSABLE MATING-TYPE CASSETTES OF FISSION YEAST
REARRANGEMENTS OF THE TRANSPOSABLE MATING-TYPE CASSETTES OF FISSION YEAST
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DOI:
10.1002/j.1460-2075.1984.tb01855.x
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发表时间:
1984-01-01
期刊:
影响因子:
11.4
通讯作者:
KLAR, AJS
中科院分区:
文献类型:
--
作者:
BEACH, DH;KLAR, AJS
The fission yeast, S. pombe, switches mating type every few cell divisions. Switching is controlled by the genes of the mating-type locus, which consists of 3 components, mat1, mat2-P and mat3-M, each separated by .apprx. 15 kilobases. Copy transposition of P (Plus) or M (Minus) information from mat2-P or mat3-M into the expression locus mat1 mediates cell type switching. The mating-type locus undergoes events at high frequency (10-2-10-6) which stabilize one or other mating type. These events are rearrangements which result in deletion or insertion of DNA between cassettes.