A-16686, A NEW ANTIBIOTIC FROM ACTINOPLANES .1. FERMENTATION, ISOLATION AND PRELIMINARY PHYSICOCHEMICAL CHARACTERISTICS
A-16686, A NEW ANTIBIOTIC FROM ACTINOPLANES .1. FERMENTATION, ISOLATION AND PRELIMINARY PHYSICOCHEMICAL CHARACTERISTICS
复制标题
DOI：
10.7164/antibiotics.37.309
复制
发表时间：
1984-01-01
影响因子：
3.3
通讯作者：
PARENTI, F
中科院分区：
文献类型：
--
作者：
CAVALLERI, B;PAGANI, H;PARENTI, F
游动放线菌ATCC 33076（一种新菌株）产生一种抗生素A-16686，它是一种由3种含有氯代苯基和D-甘露糖的多肽组成的复合物。复合物和单一组分对革兰氏阳性菌具有较好的抗菌活性。A-16686特异性抑制细菌细胞壁的合成。
Actinoplanes sp. ATCC 33076 (a new strain) produced an antibiotic, designated A-16686, which was a complex of 3 closely-related polypeptides containing chlorinated phenyl moieties and D-mannose. The complex and the single fractions possessed good activity against gram-positive bacteria. A-16686 specifically inhibited synthesis of the bacterial cell wall.