Combined liver‐kidney transplantation in children: Indications and outcome
Combined liver‐kidney transplantation in children: Indications and outcome
复制标题
儿童肝肾联合移植：适应症和结果
DOI：
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发表时间：
2008
影响因子：
1.3
通讯作者：
W. Concepción
中科院分区：
文献类型：
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作者：
S. Sutherland;S. Alexander;M. Sarwal;W. Berquist;W. Concepción
翻译后摘要：虽然它仍然是一个相对罕见的程序在儿童中，CLKT已成为一个可行的选择一组严重的肝脏和肾脏疾病的儿科患者。 大多数是为罕见的原发性疾病，如PH1，但少数是在不确定的病因和预后的并发肝和肾衰竭的情况下进行。本文综述了儿童CLKT的适应证和结局。虽然它侧重于同时影响肝脏和肾脏功能的特定原发性疾病，但它也解决了基于伴随的肝脏和肾脏衰竭的适应症，例如肝肾综合征。
Abstract: Although it remains a relatively infrequent procedure in children, CLKT has become a viable option for a select group of pediatric patients with severe liver and kidney disease. Most are performed for rare primary diseases such as PH1, but a selected few are performed in the setting of concomitant hepatic and renal failure of uncertain etiology and prognosis. This article reviews the indications for and outcomes following CLKT in children. While it focuses on the specific primary diseases which impact liver and kidney function simultaneously, it addresses the indications based on concomitant hepatic and renal failure, such as seen in the hepatorenal syndrome, as well.