Transient RLS during pregnancy is a risk factor for the chronic idiopathic form
Transient RLS during pregnancy is a risk factor for the chronic idiopathic form
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DOI：
10.1212/wnl.0b013e318200d779
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发表时间：
2010-12-07
期刊：
影响因子：
9.9
通讯作者：
Manconi, M.
中科院分区：
文献类型：
--
作者：
Cesnik, E.;Casetta, I.;Manconi, M.
目的：妊娠是短暂性不宁腿综合征的危险因素，通常在产后恢复。本调查的目的是调查是否在怀孕期间的不宁腿综合征的危险因素，为以后的发展不宁腿syndrome.Methods：一个长期的后续研究，计划作为一个扩展以前的调查不宁腿综合征在怀孕期间，进行了。平均间隔6.5年后，207名产妇再次接触，比较不宁腿综合征的发病率之间的受试者谁从来没有经历过的症状与那些谁报告不宁腿综合征在以前调查pregnancy.Results：74名妇女谁经历过不宁腿综合征在以前的怀孕，133人没有，被列入本研究。不宁腿综合征的发病率是56%人/年的妇女经历了短暂的怀孕不宁腿综合征的形式，和12.6%人/年的受试者谁没有，与一个显着的4倍增加的风险发展慢性不宁腿综合征的妇女谁提出不宁腿在以前的怀孕。考虑到在随访期间进一步的新怀孕，不宁腿症状在58%的病例中再次出现，而在从未经历过不宁腿综合征的女性中，只有3%的女性首次出现不宁腿症状。暂时性妊娠不宁腿综合征形式是未来发展为慢性特发性不宁腿综合征形式的重要风险因素，并在未来怀孕时进行新的暂时性子宫内膜异位症。神经病学（R）2010;75：2117-2120
Objective: Pregnancy is a risk factor for transient restless legs syndrome, which usually recovers during the postdelivery period. The goal of the present survey is to investigate whether restless legs syndrome during pregnancy represents a risk factor for later development of restless legs syndrome.Methods: A long-term follow-up study, planned as an extension of a previous survey on restless legs syndrome during pregnancy, was carried out. After a mean interval of 6.5 years, 207 parous women were contacted again to compare the incidence of restless legs syndrome among subjects who never experienced the symptoms with those who reported restless legs syndrome during the previously investigated pregnancy.Results: Seventy-four women who experienced restless legs syndrome during previous pregnancy, and 133 who did not, were included in the study. The incidence of restless legs syndrome was 56% person/year in women who experienced the transient pregnancy restless legs syndrome form, and 12.6% person/year in subjects who did not, with a significant 4-fold increased risk of developing chronic restless legs syndrome in women who presented restless legs in the previous pregnancy. Considering further new pregnancies during the follow-up period, the restless legs symptoms reappeared in 58% of the cases, while they emerged for the first time in only 3% of women who had never experienced restless legs syndrome.Conclusions: The transient pregnancy restless legs syndrome form is a significant risk factor for the development of a future chronic idiopathic restless legs syndrome form, and for a new transient symptomatology in a future pregnancy. Neurology (R) 2010;75:2117-2120