LONG-TERM TRENDS IN INTRAOCULAR PRESSURE AFTER PARS PLANA VITRECTOMY
LONG-TERM TRENDS IN INTRAOCULAR PRESSURE AFTER PARS PLANA VITRECTOMY
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DOI：
10.1097/iae.0b013e3181ff0d5a
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发表时间：
2011-04-01
影响因子：
3.3
通讯作者：
Sternberg, Paul, Jr.
中科院分区：
文献类型：
--
作者：
Lalezary, Maziar;Kim, Stephen Jae;Sternberg, Paul, Jr.
目的：探讨玻璃体切除术对眼压的影响。方法：回顾性队列研究。对101例非紧急玻璃体切除术患者的101只眼的医疗记录进行了回顾，以了解开角型青光眼的发生率、IOP较基线升高bb4mmhg、IOP较基线的变化以及白内障的形成。记录术前和末次测量的IOPs。基线风险特征包括晶状体状态和糖尿病。主要观察指标为：1)开角型青光眼的发生率；2)眼压升高bb0.4 mmHg；3)眼压变化。结果：平均随访49个月（范围12 ~ 105个月）。平均基线IOP为15.3 mmHg，平均最终IOP为15.8 mmHg （P=0.3）。在最近的检查中，35只眼睛的IOP较基线有所下降，14只眼睛没有变化，52只眼睛的IOP有所增加。4只研究眼新诊断为高眼压。研究中没有眼出现开角型青光眼，也没有眼需要药物、激光或手术治疗。4年和8年IOP升高的发生率分别为7%和34%。对66例患者进行亚组分析，将研究眼与未做玻璃体切除的眼进行比较，结果显示，IOP升高率无显著差异（P=0.85）。糖尿病和假性晶状体均与IOP升高无关。结论：在这个系列中，玻璃体切除术即使在摘除晶状体后也不会增加IOP。中国生物医学工程学报（英文版），2011
Purpose: To evaluate the effect of vitrectomy on intraocular pressure (IOP).Methods: Retrospective cohort study. Medical records of 101 eyes of 101 patients undergoing nonemergent vitrectomy were reviewed for rates of open-angle glaucoma, increased IOP of >4 mmHg from baseline, change in IOP from baseline, and cataract formation. Preoperative and last measured IOPs were recorded. Baseline risk characteristics including lens status and diabetes were analyzed. Main outcome measures were 1) incidence of open-angle glaucoma; 2) increase in IOP of >4 mmHg; and 3) change in IOP.Results: Mean follow-up was 49 months (range, 12-105 months). Mean baseline IOP was 15.3 mmHg, and mean final IOP was 15.8 mmHg (P=0.3). At the most recent examination, 35 study eyes had a decrease in IOP from baseline, while 14 eyes had no change and 52 eyes had an increase in IOP. Four study eyes were newly diagnosed with ocular hypertension. No study eye developed open-angle glaucoma or required medical, laser, or surgical treatment for glaucoma. Incidence of increased IOP of >4 was 7% at 4 years and 34% at 8 years. Subgroup analysis of 66 patients comparing study eyes with nonvitrectomized fellow eyes demonstrated no significant difference in rates of increased IOP of >4 (P=0.85). Neither diabetes nor pseudophakia was associated with significantly increased IOP.Conclusion: In this series, vitrectomy does not appear to increase IOP even after removal of the crystalline lens.RETINA 31: 679-685, 2011