Revisiting the role of introgression vs shared ancestral polymorphisms as key processes shaping genetic diversity in the recently separated sibling species of the Anopheles gambiae complex
Revisiting the role of introgression vs shared ancestral polymorphisms as key processes shaping genetic diversity in the recently separated sibling species of the Anopheles gambiae complex
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DOI：
10.1038/sj.hdy.6800377
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发表时间：
2004-02-01
期刊：
影响因子：
3.8
通讯作者：
Lehmann, T
中科院分区：
文献类型：
--
作者：
Donnelly, MJ;Pinto, J;Lehmann, T
种间杂交在害虫物种进化中的作用知之甚少。在蚊子病媒中，这一点特别重要，因为杀虫剂抗药性的演变和拟释放的转基因菌株对疟疾寄生虫具有抗药性。在这项研究中，我们以一种新的方式应用群体遗传学方法来确定线粒体DNA序列是否在密切相关的非洲疟疾媒介冈比亚按蚊和A.阿拉伯的。我们的研究结果表明，物种形成的地质最近和祖先的单倍型在ND5位点保留在这两个物种。此外，通过比较异域和同域群体中的单倍型频率，提示了A. arabiensis转化为A.冈比亚。
The role of interspecific hybridisation in the evolution of pest species is poorly understood. In mosquito disease vectors this is of particular importance due to the evolution of insecticide resistance and the proposed release of transgenic strains that are refractory to the malaria parasite. In this study, we apply population genetic methods in a novel manner to determine whether mitochondrial DNA sequences have introgressed between the closely related African malaria vectors Anopheles gambiae and A. arabiensis. Our results suggest that speciation was geologically recent and ancestral haplotypes at the ND5 locus are retained in both species. In addition, comparing haplotype frequencies in allopatric and sympatric populations, suggest locale specific unidirectional introgression of mitochondria from A. arabiensis into A. gambiae.