Extensive cerebral white matter involvement in a patient with NMO spectrum disorder

Extensive cerebral white matter involvement in a patient with NMO spectrum disorder
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DOI:
10.1177/1352458514536253
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发表时间:
2014-09-01
影响因子:
5.8
通讯作者:
Labauge, Pierre
Labauge, Pierre
中科院分区:
医学2区
文献类型:
--
作者:
Ayrignac, Xavier;Daliere, Clarisse Carra;Labauge, Pierre

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在高达60%的NMO患者中描述了异常的脑MRI。然而,白色物质T2高信号很少被观察到。我们报告的情况下,一个49岁的妇女与长期的视神经肌萎缩症(NMO)频谱障碍和弥漫性脑白色物质T2加权高信号。我们的病例表明,一些NMO患者可以逐步发展为广泛的脑受累。
Abnormal brain MRI has been described in up to 60% of patients with NMO patients. However, white matter T2 hyperintensities have been rarely observed. We report the case of a 49-year-old woman with long-lasting neuromyelitis optica (NMO) spectrum disorder and diffuse cerebral white matter T2-weighted hyperintensities. Our case suggests that some NMO patients can progressively develop l extensive cerebral involvement.