Trends in soil sorption coefficients within common antimicrobial families
Trends in soil sorption coefficients within common antimicrobial families
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DOI：
10.1016/j.chemosphere.2010.03.017
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发表时间：
2010-05-01
期刊：
影响因子：
8.8
通讯作者：
MacKay, Allison A.
中科院分区：
文献类型：
--
作者：
Figueroa-Diva, Raquel A.;Vasudevan, Dharni;MacKay, Allison A.
使用批量吸附技术测量了 pH 4.5 至 8.5 之间的七种土壤中氟喹诺酮、四环素和磺酰胺抗菌化合物的吸附系数 (K-d)。选择的土壤包含一系列阳离子交换能力（CEC）、铁和铝的氧化物以及有机物含量。对于大多数土壤-pH 对来说，恩诺沙星、诺氟沙星和环丙沙星的 K-d 值彼此相差在 2 倍以内（0.3 个对数单位）。对于两种最富含铝硅酸盐粘土的土壤，在 pH 8.5 时观察到恩诺沙星的吸附低于诺氟沙星或环丙沙星的吸附，这可能是由于酸解离常数的化合物差异，导致恩诺沙星的阴离子种类丰度更高。对于每个土壤 pH 值对，四环素、土霉素和金四环素的 K-d 值也在 2 倍以内。测量的四环素和氟喹诺酮化合物 K-d 值可以使用已发表的经验多线性回归模型在 2 倍内估计。相比之下，磺酰胺 K-d 值因化合物而异，正如对主要与土壤有机质相互作用的山梨酸盐所预期的那样。这项研究的结果表明，取代基对四环素和氟喹诺酮家族化合物的吸附相互作用影响不大，这些化合物主要通过阳离子交换、表面络合和阳离子桥吸附机制与土壤相互作用。 (C) 2010 Elsevier Ltd. 保留所有权利。
Sorption coefficients (K-d) of fluoroquinolone, tetracycline, and sulfonamide antimicrobial compounds were measured for seven soils between pH 4.5 and 8.5 using batch sorption techniques. Soils were chosen to encompass a range of cation exchange capacity (CEC), iron and aluminum oxide and organic matter contents. For most soil-pH pairs, enrofloxacin, norfloxacin, and ciprofloxacin K-d values were within a factor of 2 (0.3 log units) of each other. Lower enrofloxacin sorption than norfloxacin or ciprofloxacin sorption was observed at pH 8.5 for the two most aluminosilicate clay-rich soils, likely due to compound differences in acid dissociation constants, yielding greater anion species abundance for enrofloxacin. Tetracycline, oxytetracycline and chlortetracycline K-d values also were within a factor of 2 for each soil-pH pair. Measured tetracycline and fluoroquinolone compound K-d values could be estimated within a factor of 2 using published empirical multi-linear regression models. In contrast, sulfonamide K-d values varied among compounds, as expected for sorbates that interact primarily with soil organic matter. Results of this research indicate that substituent groups have little effect on sorption interactions of compounds from the tetracycline and fluoroquinolone family that interact with soils primarily through cation exchange, surface complexation and cation bridging sorption mechanisms. (C) 2010 Elsevier Ltd. All rights reserved.