Assessment and treatment of depression in patients with cardiovascular disease:: National Heart, Lung, and Blood Institute working group report
Assessment and treatment of depression in patients with cardiovascular disease:: National Heart, Lung, and Blood Institute working group report
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DOI：
10.1097/01.psy.0000233233.48738.22
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发表时间：
2006-09-01
影响因子：
3.3
通讯作者：
Suls, Jerry M.
中科院分区：
文献类型：
--
作者：
Davidson, Karina W.;Kupfer, David J.;Suls, Jerry M.
目的：国家心脏、肺和血液研究所召集了一个跨学科的专家工作组，以制定评估和治疗冠心病（CHD）患者抑郁症的建议。方法：征求专家意见。结果:我们目前的建议是：采用贝克抑郁量表（Beck Depression Inventory-I）进行抑郁症和冠心病的流行病学研究，采用患者健康问卷（Patient Health Questionnaire）两项版本进行试验资格筛选，采用抑郁症访谈和结构化汉密尔顿量表（DISH）进行试验纳入的诊断确定，采用汉密尔顿评定量表，这是DISH的一部分。在任何试验中均可用于抑郁症状减轻和缓解标准。我们进一步建议进行一项随机对照试验，以确定选择性血清素再摄取抑制剂、心理治疗或联合治疗是否可以降低冠心病患者抑郁相关的冠心病事件和死亡率的风险。结论：本报告总结了工作组提出的建议，并讨论了每项建议的理由、评估和治疗替代方法的优缺点，以及对该领域未来研究的影响。
Objective: The National Heart, Lung, and Blood Institute convened an interdisciplinary working group of experts to develop recommendations for the assessment and treatment of depression in patients with coronary heart disease (CHD). Method: Consensus of experts. Results: Our current recommendations are that the Beck Depression Inventory-I be employed for epidemiological studies of depression and CHD, that the Patient Health Questionnaire 2-item version be employed for screening for trial eligibility, that the Depression Interview and Structured Hamilton (DISH) be employed for diagnostic ascertainment for trial inclusion, and that the Hamilton rating scale, which is part of the DISH, be employed for both depression symptom reduction and the remission criterion in any trial. We further recommend that a randomized controlled trial be undertaken to determine whether selective serotonin reuptake inhibitors, psychotherapy, or combined treatment can reduce the risk of CHD events and mortality associated with depression in CHD patients. Conclusions: This report summarizes the recommendations made by the working group and discusses the rationale for each recommendation, the strengths and weaknesses of alternative approaches to assessment and treatment, and the implications for future research in this area.