Silent Seizures in Sick Infants in Early Life
Silent Seizures in Sick Infants in Early Life
复制标题
患病婴儿生命早期的无症状癫痫发作
DOI：
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发表时间：
1985
期刊：
影响因子：
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通讯作者：
N. W. Swenningsen
中科院分区：
文献类型：
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作者：
L. Hellström;I. Rosén;N. W. Swenningsen
摘要。应用脑功能监测仪（CFM）对87例新生儿重症监护下的脑电活动进行了监测。共有26名婴儿有反复发作活动的电体征。在这些婴儿中，14例有一小时或更长时间的无症状癫痫发作，即CFM的典型癫痫发作模式，没有临床症状或抽搐迹象。在大多数病例中，无症状发作的发生及其模式与临床状况和治疗的关系是不可预测的。除了外表安静的婴儿全身无力或软弱无力外，这些婴儿没有表现出临床发作或阵挛性抽搐。研究结果表明，小婴儿的抗惊厥治疗可能不足，需要重新评估，因为无声发作对脑功能和活动的长期影响仍不确定。
ABSTRACT. Cerebral electric activity was surveilled with a Cerebral Function Monitor (CFM) technique in 87 newborn infants under neonatal intensive care. A total of 26 infants had electrographical signs of repeated seizure activity. Among these infants 14 had periods of one hour or more of silent seizures, i.e. typical pattern of ictal epileptic activity on CFM without clinical symptoms or signs of convulsions. The occurrence of silent seizures and their pattern in relation to the clinical condition and management was unpredictable in most cases. Besides general limpness or flaccidity in an outward quiet baby these infants showed no clinical fits or clonic convulsions. The findings indicate that anticonvulsive therapy in small infants may be insufficient and need re‐evaluation, since the long‐term effect of silent seizures on cerebral function and activity is still uncertain.
癫痫性脑损伤：病理生理学和神经化学病理学。
影响因子：
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作者：
Siesjo,BK;Wieloch,T
通讯作者：
Wieloch,T