Controlling Ebola: key role of Ebola treatment centres.
Controlling Ebola: key role of Ebola treatment centres.
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DOI：
10.1016/s1473-3099(14)71086-2
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发表时间：
2015-03
期刊：
影响因子：
--
通讯作者：
Viboud C
中科院分区：
文献类型：
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作者：
Chowell G;Viboud C
最初被认为是几内亚森林地区的埃博拉病毒病自我限制的爆发，已成为引起国际关注的前所未有的流行病，在西非部分地区继续不减地蔓延。缺乏公共卫生基础设施，加上病毒检测和实施控制干预措施的延误，导致埃博拉病毒病在一个没有这种疾病的地区广泛传播。3与以往的国际卫生危机，如严重急性呼吸系统综合症流行病和2009年流感大流行一样，数学模型在指导公共卫生应对埃博拉病毒病和监测控制干预措施的有效性方面发挥了重要作用。尽管早期的建模工作依赖于区隔均匀混合模型，但Stefano Merler及其同事在《柳叶刀传染病》（the Lancet Infectious Diseases）上发表的研究使用了微观模拟模型来捕捉病毒传播动力学的空间异质性
What initially was perceived to be a self-limited outbreak of Ebola virus disease in a forested area of Guinea has become an unprecedented epidemic of international concern that continues to spread unabated in parts of west Africa. 1, 2 A lack of public health infrastructure together with delays in virus detection and implementation of control interventions have contributed to the widespread transmission of Ebola virus disease in a region inexperienced with this disease. 3 As in previous international health crises, such as the severe acute respiratory syndrome epidemic and the 2009 influenza pandemic, mathematical models are proving instrumental to guide the public health response against Ebola virus disease and monitor the effectiveness of control interventions. 4, 5 Whereas earlier modelling efforts have relied on compartmental homogeneous-mixing models, 6–8 the study by Stefano Merler and colleagues, 9 reported in The Lancet Infectious Diseases, uses a microsimulation model to capture spatial heterogeneity in the transmission dynamics of