Reporting clinical trials in general surgical journals.
Reporting clinical trials in general surgical journals.
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在普通外科期刊上报告临床试验。
作者：
J. D. Emerson;B. Mcpeek;F. Mosteller
读者需要有关临床试验的设计和分析的信息来评估和解释其结果。我们回顾了 1981 年 7 月至 1982 年 6 月期间发表在 6 种普通外科期刊上的 84 项治疗试验，并评估了设计和分析的 11 个重要方面的报告。总体而言，11 个项目中，59% 明确报告，5% 讨论模糊，36% 未报告。因此，普通外科期刊的报道频率与其他人发现的四种普通医学期刊的 56% 相似。报告最好用于随机分配（89%）、失访（86%）和统计分析（85%）。报告最缺乏的是用于生成治疗分配的方法（27%）和检测治疗差异的调查能力（5%）。我们建议临床期刊提供临床试验报告中包含的重要项目列表。
Readers need information about the design and analysis of a clinical trial to evaluate and interpret its findings. We reviewed 84 therapeutic trials appearing in six general surgical journals from July 1981 through June 1982 and assessed the reporting of 11 important aspects of design and analysis. Overall, 59% of the 11 items were clearly reported, 5% were ambiguously discussed, and 36% were not reported. The frequency of reporting in general surgical journals is thus similar to the 56% found by others for four general medical journals. Reporting was best for random allocation (89%), loss to follow-up (86%), and statistical analyses (85%). Reporting was most deficient for the method used to generate the treatment assignment (27%) and for the power of the investigation to detect treatment differences (5%). We recommend that clinical journals provide a list of important items to be included in reports on clinical trials.
癌症临床试验论文发表指南：编辑和作者的责任。
DOI：
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发表时间：
1983
期刊：
Progress in clinical and biological research
影响因子：
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作者：
Zelen,M
通讯作者：
Zelen,M