Contribution of area MT to stereoscopic depth perception: Choice-related response modulations reflect task strategy
Contribution of area MT to stereoscopic depth perception: Choice-related response modulations reflect task strategy
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DOI：
10.1016/s0896-6273(04)00186-2
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发表时间：
2004-04-22
期刊：
影响因子：
16.2
通讯作者：
DeAngelis, GC
中科院分区：
文献类型：
--
作者：
Uka, T;DeAngelis, GC
由于感觉皮层中调节特性的多样性，只有一小部分神经元参与特定的任务。表征与行为功能相关的神经元的调节特性，对于理解如何从感觉地图中“读出”活动以指导决策至关重要。我们记录了猴子在执行深度辨别任务时中颞叶（MT）神经元的反应，并描述了MT反应与行为选择之间的联系。具有奇对称（“近”、“远”）视差调节的MT神经元的试验对试验的反应波动可以预测猴子的选择，而具有偶数对称调节的神经元的反应则不能。这一结果不能用神经元敏感性或我们所研究的MT神经元的任何其他响应特性来解释，而是简单地用猴子在训练过程中学习的任务策略来解释。我们认为这种方法提供了一种生理手段来探索任务策略是如何在大脑中实现的。
Due to the diversity of tuning properties in sensory cortex, only a fraction of neurons are engaged in a particular task. Characterizing the tuning properties of neurons that are functionally linked to behavior is essential for understanding how activity is "read out" from sensory maps to guide decisions. We recorded from middle temporal (MT) neurons while monkeys performed a depth discrimination task, and we characterized the linkage between MT responses and behavioral choices. Trial-to-trial response fluctuations of MT neurons with odd-symmetric ("Near," "Far") disparity tuning were predictive of monkeys' choices, whereas responses of neurons with even-symmetric tuning were not. This result cannot be explained by neuronal sensitivity or any other response property of MT neurons that we examined but is simply explained by the task strategy that monkeys learned during training. We suggest that this approach provides a physiological means to explore how task strategies are implemented in the brain.