Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence
Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence
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DOI：
10.1039/c9cc09064a
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发表时间：
2020-02-11
影响因子：
4.9
通讯作者：
Sutherland, Andrew
中科院分区：
文献类型：
--
作者：
Bell, Jonathan D.;Harkiss, Alexander H.;Sutherland, Andrew
本文报道了一类新的带有吡唑并喹唑啉刚性发色团的α-氨基酸的合成及其物理性质。氨基酸侧链的构象约束导致高的发射量子产率，而通过近红外激发的双光子诱导荧光的演示表明它们在敏感的生物成像应用中的潜力。
The synthesis and photophysical properties of a new class of alpha-amino acid bearing a rigid pyrazoloquinazoline chromophore are described. Confromational constraint of the amino acid side-chains resulted in high emission quantum yields, while the demonstration of two-photon-induced fluorescence via near-IR excitation signifies their potential for sensitive bioimaging applications.