The use of oscillatory signals in the study of genetic networks

The use of oscillatory signals in the study of genetic networks
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DOI:
10.1073/pnas.0403790102
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发表时间:
2005-05-17
影响因子:
11.1
通讯作者:
Wong, WH
Wong, WH
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Lipan, O;Wong, WH

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遗传网络的结构是通过研究其对外部刺激(输入信号)的反应来揭示的。我们提出了一个理论,通过线性随机遗传网络的输入信号的传播。我们发现,有重要的优势,在使用振荡信号的步骤或脉冲信号,系统可能会进入一个纯波动共振为一个特定的输入频率。
The structure of a genetic network is uncovered by studying its response to external stimuli (input signals). We present a theory of propagation of an input signal through a linear stochastic genetic network. We found that there are important advantages in using oscillatory signals over step or impulse signals and that the system may enter into a pure fluctuation resonance for a specific input frequency.