High frequency oscillations evoked by peripheral magnetic stimulation
High frequency oscillations evoked by peripheral magnetic stimulation
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DOI：
10.1109/iembs.2011.6090269
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发表时间：
2011-12
期刊：
影响因子：
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通讯作者：
S. Biller;L. Simon;P. Fiedler;D. Strohmeier;J. Haueisen
中科院分区：
文献类型：
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作者：
S. Biller;L. Simon;P. Fiedler;D. Strohmeier;J. Haueisen
体感诱发电位（SEP）和/或场（SEF）的分析是研究外周和中枢人类神经系统功能的公认和重要的工具。诱发SEP/SEF的标准技术是通过使用双极电刺激来刺激正中神经。我们的目标是一种替代刺激技术，能够刺激深层神经结构，同时减少患者的压力和错误的敏感性。在目前的研究中，我们应用商业经颅磁刺激系统进行正中神经的外周磁刺激。我们比较了同时记录的EEG信号的结果，以证明我们的技术的适用性，以唤起包括低频成分（LFC）以及高频振荡（HFO）的SEP。因此，我们比较了14名健康志愿者在电刺激和磁刺激后SEP的振幅、潜伏期和时频特性。低频成分和高频振荡都被检测到。将HFO叠加在初级皮质反应N20上。统计学分析显示，磁刺激后LFC和HFO成分的振幅显著降低，波幅增加。这些差异表明磁刺激无法引起超大反应。一项心理感知评估显示，14名志愿者中有12人对磁刺激不那么不愉快。总之，我们表明，LFC和HFO组件相关的正中神经刺激可以诱发外周磁刺激。
The analysis of somatosensory evoked potentials (SEP) and / or fields (SEF) is a well-established and important tool for investigating the functioning of the peripheral and central human nervous system. A standard technique to evoke SEPs / SEFs is the stimulation of the median nerve by using a bipolar electrical stimulus. We aim at an alternative stimulation technique enabling stimulation of deep nerve structures while reducing patient stress and error susceptibility. In the current study, we apply a commercial transcranial magnetic stimulation system for peripheral magnetic stimulation of the median nerve. We compare the results of simultaneously recorded EEG signals to prove applicability of our technique to evoke SEPs including low frequency components (LFC) as well as high frequency oscillations (HFO). Therefore, we compare amplitude, latency and time-frequency characteristics of the SEP of 14 healthy volunteers after electric and magnetic stimulation. Both low frequency components and high frequency oscillations were detected. The HFOs were superimposed onto the primary cortical response N20. Statistical analysis revealed significantly lower amplitudes and increased latencies for LFC and HFO components after magnetic stimulation. The differences indicate the inability of magnetic stimulation to elicit supramaximal responses. A psycho-perceptual evaluation showed that magnetic stimulation was less unpleasant for 12 out of the 14 volunteers. In conclusion, we showed that LFC and HFO components related to median nerve stimulation can be evoked by peripheral magnetic stimulation.