The association between smoking and unfavorable outcomes in acute ischemic stroke patients with mechanical thrombectomy
The association between smoking and unfavorable outcomes in acute ischemic stroke patients with mechanical thrombectomy
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吸烟与机械取栓急性缺血性脑卒中患者不良结局的关系
DOI：
10.18332/tid/119229
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发表时间：
2020-04
影响因子：
3.7
通讯作者：
Zou JianJun
中科院分区：
文献类型：
--
作者：
Zhao Zhihong;Zhao Zheng;Zheng Xiaohan;Li Xiang;Li Xuemei;Huang Chaoping;Shan Yajie;Nyame Linda;Ibrahim Mako;Gao Xiaoping;Liang Hui;Hu Jue;Zou JianJun
INTRODUCTION Little is known about the relationship between smoking and clinical outcomes in acute ischemic stroke (AIS) patients undergoing mechanical thrombectomy (MT). The outcomes could depend on different stroke subtypes. The aim of this study was to investigate whether smoking affected differently the outcomes in patients with different stroke subtypes who received MT. METHODS AIS patients who underwent MT were prospectively enrolled from three hospitals between January 2014 and December 2018. Smokers were defined as current users of cigarettes. The stroke subtypes were classified according to TOAST criteria. Outcome measurements included treatment effects, intracerebral hemorrhage (ICH), and functional outcomes at 3 months. The effects of smoking on outcomes were assessed by logistic regression analysis. RESULTS A total of 128 AIS patients with MT were enrolled, including 64 smokers and 64 non-smokers. Logistic regression analysis indicated that smoking was related to higher risk of In-hospital ICH (OR=4.31; 95% CI: 1.10–16.96; p=0.036) in patients with cardioembolism subtype. Furthermore, smoking was also associated with lower rates of mild stroke at discharge (OR=0.07; 95% CI: 0.02–0.31; p<0.001) and functional independence (OR=0.13; 95% CI: 0.03–0.56; p=0.006) in patients with cardioembolism subtype. CONCLUSIONS In AIS patients undergoing MT, smoking could be related to a higher risk of In-hospital ICH and lower rates of mild stroke at discharge and functional independence if their stroke subtype is cardioembolism.
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DOI：
10.1016/s0749-4041(08)79111-5
发表时间：
2009
期刊：
Yearbook of Vascular Surgery
影响因子：
--
作者：
G. Moneta
通讯作者：
G. Moneta
影响因子：
6
作者：
Hunter, KA;Garlick, PJ;McNurlan, MA
通讯作者：
McNurlan, MA
DOI：
10.1016/s0513-5117(09)79035-0
发表时间：
2009
期刊：
Yearbook of Neurology and Neurosurgery
影响因子：
--
作者：
A. Rabinstein
通讯作者：
A. Rabinstein
影响因子：
1.5
作者：
Monique Lloyd
通讯作者：
Monique Lloyd
影响因子：
158.5
作者：
Hacke, Werner;Kaste, Markku;Toni, Danilo
通讯作者：
Toni, Danilo