Cutaneous complications after transcatheter arterial treatment for hepat ocellular carcinoma via the internal mammary artery : how to avoid this complication
Cutaneous complications after transcatheter arterial treatment for hepat ocellular carcinoma via the internal mammary artery : how to avoid this complication
复制标题
经乳内动脉经导管动脉治疗肝眼细胞癌后的皮肤并发症：如何避免这种并发症
DOI：
10.1007/s11604-011-0559-9
复制
发表时间：
2011
期刊：
影响因子：
2.1
通讯作者：
Awai K
中科院分区：
文献类型：
--
作者：
Kajiwara K;Kakizawa H;Takeuchi N;Toyota N;Hieda M;Ishikawa M;Tanitame K;Tani G;Suzuki T;Fujikawa K;Aikata H;Chayama K;Awai K
为了降低经乳内动脉（IMA）经导管动脉治疗肝细胞癌（HCC）后皮肤并发症的发生率，我们回顾性评估了并发症。材料和方法我们回顾了14例患者的18例HCC的皮肤并发症，这些患者接受了17次经IMA的治疗程序，包括选择性经导管动脉碘油灌注化疗（Lip-TAI）（n= 3），选择性Lip-TAI +经导管动脉栓塞（TAE）（n= 3）、非选择性Lip-TAI（n= 1）、非选择性Lip-TAI + TAE（n= 5）和非选择性TAE（n= 5）。填充和非填充的皮下血管与碘油检查术后计算机断层扫描（CT）scannes. Results皮疹（n= 3）和溃疡（n= 1）发生后，4 17（24%）的程序：两个三个选择性Lip-TAI程序和两个五个非选择性Lip-TAI + TAE程序。选择性Lip-TAI手术中肿瘤大小的化疗药物剂量高于选择性Lip-TAI + TAE手术。皮肤并发症后，遇到两个三个程序填充，但没有任何8个程序后，没有filling.ConclusionA低剂量的化疗药物进行选择性程序时，通过IMA HCC的风险可能较小。如果是非选择性的，单独的TAE可能风险较小。术后CT检查有助于预测皮肤并发症。
PurposeTo lower the rate of cutaneous complications after transcatheter arterial treatment for hepatocellular carcinoma (HCC) via the internal mammary artery (IMA) we retrospectively assessed the complications.Materials and methodsWe reviewed cutaneous complications in 14 patients with 18 HCCs who had undergone 17 treatment procedures via the IMA, including selective transcatheter arterial infusion chemotherapy with Lipiodol (Lip-TAI) (n= 3), selective Lip-TAI + transcatheter arterial embolization (TAE) (n= 3), nonselective Lip-TAI (n= 1), nonselective Lip-TAI + TAE (n= 5), and nonselective TAE (n= 5). The filling and nonfilling of subcutaneous vessels with Lipiodol was examined on postoperative computed tomography (CT) scans.ResultsSkin rash (n= 3) and ulceration (n= 1) occurred after 4 of 17 (24%) procedures: two of three selective Lip-TAI procedures and two of five nonselective Lip-TAI + TAE procedures. The doses of chemotherapeutic agents for tumor sizes in selective Lip-TAI procedures were higher than those in selective Lip-TAI + TAE procedures. Cutaneous complications were encountered after two of three procedures with filling but not after any of eight procedures without filling.ConclusionA lower dose of chemotherapeutic agents may be less risky when undertaking a selective procedure via the IMA for HCC. If nonselective, TAE alone may be less risky. Postoperative CT may be helpful for predicting cutaneous complications.