Management of Lupus Nephritis: New Treatments and Updated Guidelines.
Management of Lupus Nephritis: New Treatments and Updated Guidelines.
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DOI：
10.34067/kid.0000000000000230
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发表时间：
2023-10-01
期刊：
影响因子：
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通讯作者：
Jefferson JA
中科院分区：
文献类型：
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作者：
Avasare R;Drexler Y;Caster DJ;Mitrofanova A;Jefferson JA
狼疮性肾炎的治疗在过去的几年里有了很大的发展。在这里，我们提供了临床试验的全面回顾，这些临床试验构成了肾脏疾病的基础：改善全球结果和EULAR/ERA-EDTA更新指南和当前的试验，这些试验将在未来几年改变狼疮性肾炎治疗的前景。此外，我们还强调了与治疗费用、耐药疾病和特定治疗的下游不良反应有关的问题。
Management of lupus nephritis has evolved considerably over the past years. Here, we provide a comprehensive review of clinical trials that form the basis for the Kidney Disease: Improving Global Outcomes and EULAR/ERA-EDTA updated guidelines and present day trials that will change the landscape of lupus nephritis therapy in years to come. In addition, we highlight the issues related to cost of therapy, resistant disease, and downstream adverse effects of specific therapies.