Chest computed tomography and mediastinoscopy in the diagnosis of sarcoidosis-associated uveitis
Chest computed tomography and mediastinoscopy in the diagnosis of sarcoidosis-associated uveitis
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DOI：
10.1016/s0002-9394(98)00081-6
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发表时间：
1998-07-01
影响因子：
4.2
通讯作者：
Lowder, CY
中科院分区：
文献类型：
--
作者：
Kosmorsky, GS;Meisler, DM;Lowder, CY
目的：报道胸部计算机断层扫描和纵隔镜检查对老年葡萄膜炎结节病的诊断价值。两名年龄分别为73岁和70岁的白人妇女接受了葡萄膜炎的评估，包括胸部计算机断层扫描和纵隔镜检查。结果：每位女性的胸部计算机断层扫描显示纵隔淋巴结病变，并通过纵隔镜检查进行纵隔淋巴结活检。在这两例患者中，组织病理学和微生物学研究表明无菌非干酪化肉芽肿与结节病的诊断一致。结论：胸部计算机断层扫描可能有助于老年人结节性葡萄膜炎的诊断，可能比常规胸部x线摄影更敏感。通过纵隔镜检查获得的纵隔淋巴结活检的实验室研究可以证实诊断。(C) 1998年Elsevier Science Inc .版权所有
PURPOSE: To report the usefulness of chest computed tomography and mediastinoscopy in diagnosing sarcoidosis in elderly patients with uveitis,METHODS: Case reports. Two Caucasian women, aged 73 and 70 years, underwent evaluations for uveitis, which included chest computed tomography and mediastinoscopy.RESULTS: A chest computed tomographic scan of each woman disclosed mediastinal lymphadenopathy and warranted mediastinal lymph node biopsy by mediastinoscopy. In both patients, histopathologic and microbiologic studies demonstrated sterile noncaseating granulomas consistent with the diagnosis of sarcoidosis.CONCLUSIONS: The diagnosis of sarcoid-associated uveitis in the elderly may be facilitated by chest computed tomography, which may be more sensitive than conventional chest roentgenography. Laboratory studies of biopsied mediastinal nodes obtained by mediastinoscopy can confirm the diagnosis. (C) 1998 by Elsevier Science Inc, All rights reserved.