FUNCTIONAL LYMPHATIC ALTERATIONS IN PATIENTS SUFFERING FROM LIPEDEMA
FUNCTIONAL LYMPHATIC ALTERATIONS IN PATIENTS SUFFERING FROM LIPEDEMA
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DOI：
10.1177/000331979504600408
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发表时间：
1995-04-01
期刊：
影响因子：
2.8
通讯作者：
ELEUTERI, P
中科院分区：
文献类型：
--
作者：
BILANCINI, S;LUCCHI, M;ELEUTERI, P
脂肪水肿是一种几乎只发生于女性的慢性血管疾病，其特征是腿部脂肪沉积，呈“埃及柱”形状、直立性水肿、皮肤体温过低、足底支撑改变以及Stemmer征阴性。这种疾病的病因和发病机制仍然是研究的对象，治疗非常困难。许多作者都描述了形态和功能的改变 静脉造影中大静脉未受影响，皮肤弹性发生改变。作者通过动态淋巴闪烁显像对 12 名患有脂肪水肿的女性患者进行了研究，并将结果与 5 名正常受试者和 5 名特发性淋巴水肿患者的结果进行了比较，这些患者的性别和年龄与患有脂肪水肿的患者相匹配。 脂肪水肿。患有脂肪水肿的患者表现出异常的淋巴闪烁显像模式，淋巴液流动减慢，这与患有淋巴水肿的患者中发现的变化有一些相似之处。在淋巴闪烁显像中还发现了频繁的不对称性，这与临床特征的对称性形成鲜明对比。
Lipedema is a chronic vascular disease almost exclusively of female sex, characterized by the deposit of fat on the legs, with an ''Egyptian column'' shape, orthostatic edema, hypothermia of the skin, alteration of the plantar support, and negativity of Stemmer's sign.The etiology and pathogenesis of this disease are still the object of study, and therapy is very difficult.Various authors have described morphologic and functional alterations of prelymphatic structures and of lymphatic vessels.The big veins remain untouched in the phlebograms and an alteration of the skin elasticity is demonstrated.The present authors have studied by dynamic lymphoscintigraphy 12 women patients suffering from lipedema, and compared the results with those of 5 normal subjects and 5 patients suffering from idiopathic lymphedema who were sex and age matched with the patients suffering from lipedema.The patients suffering from lipedema showed an abnormal lymphoscintigraphic pattern with a slowing of the lymphatic flow that presented some analogies to the alterations found in the patients suffering from lymphedema.A frequent asymmetry was also noticed in the lymphoscintigraphic findings that is in contrast to the symmetry of the clinical profile.