Life span of common marmoset (Callithrix jacchus) at CLEA Japan breeding colony
Life span of common marmoset (Callithrix jacchus) at CLEA Japan breeding colony
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DOI：
10.1007/s10522-012-9388-1
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发表时间：
2012-08-01
期刊：
影响因子：
4.5
通讯作者：
Kitajima, Shuji
中科院分区：
文献类型：
--
作者：
Nishijima, Kazutoshi;Saitoh, Ryoichi;Kitajima, Shuji
对CLEA Japan， Inc.的一个繁殖群体中普通狨猴（Callithrix jacchus）的寿命和存活参数进行了调查。雄性绒猴的平均寿命为148.5 +/- A 6.1（平均+/- A SE）月龄(M)，显著长于雌性（111.7 +/- A 6.0 M） （P < 0.01）。此外，男性人口的死亡率分别为25%、50%、75%和90%，高于女性人口。雄性的最大寿命（259.9 M）低于雌性（262.5 M）。雌性的存活率呈现出相对持续的下降趋势；然而，雄性狨猴在前7-9年的存活率略有下降，然后急剧下降，14-16岁后存活率又略有下降，即寿命曲线与衰老的啮齿动物和人类群体相似。性别相关的寿命差异是由雌性的生殖负担引起的。本研究报告了狨猴的寿命比预期的要长，长寿动物可以成为衰老和长寿科学的有力模型。
The life span and survival parameters of the common marmoset (Callithrix jacchus) in a breeding colony at CLEA Japan, Inc. were investigated. The average life span of male marmosets was 148.5 +/- A 6.1 (mean +/- A SE) months of age (M), which was significantly longer (P < 0.01) than that of females (111.7 +/- A 6.0 M). Additionally, the male population reached 25-, 50-, 75- and 90 %-mortality at an older age than the female population. However, the maximum life span in males (259.9 M) was shorter than in females (262.5 M). The survival of females shows a relatively continuous decline; however, the male marmosets show a slight decline in survival during the first 7-9 years and then a dramatic decrease and another slight decline after 14-16 year of age in survival, i.e., a lifespan curve similar to what is observed in colonies of aging rodents and humans. The sex-associated difference in life span was caused by reproductive burden on the females. The present study reported a longer than expected life span of the marmoset, and a long-lived animal can be a powerful model for senescence and longevity sciences.