Effects of exercise training on cardiovascular function and plasma lipid, lipoprotein, and apolipoprotein concentrations in premenopausal and postmenopausal women.
Effects of exercise training on cardiovascular function and plasma lipid, lipoprotein, and apolipoprotein concentrations in premenopausal and postmenopausal women.
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运动训练对绝经前和绝经后妇女心血管功能和血浆脂质、脂蛋白和载脂蛋白浓度的影响。
DOI：
10.1161/01.atv.11.4.912
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发表时间：
1991
期刊：
影响因子：
--
通讯作者：
Rodin,J
中科院分区：
文献类型：
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作者：
Blumenthal,JA;Matthews,K;Fredrikson,M;Rifai,N;Schniebolk,S;German,D;Steege,J;Rodin,J
这项研究探讨了有氧运动对绝经前和绝经后女性血脂水平的影响。 50 名健康中年女性（平均年龄 50 岁）被随机分配进行 12 周的有氧运动（步行和慢跑）或非有氧力量运动（鹦鹉螺循环训练）。评估了总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和极低密度脂蛋白胆固醇的浓度，以及载脂蛋白 (apo) A-I、apo A-II、apo B 和甘油三酯。为了记录有氧能力的变化，在运动计划之前和之后进行了最大跑步机测试和呼出气体分析。有氧运动可使峰值摄氧量提高 18%。有氧运动组女性的摄氧量有所增加，从 26.7 毫升/公斤/分钟增加到 31.4 毫升/公斤/分钟（p 小于 0.0001），而力量训练组女性的摄氧量没有变化（前后为 25.8 毫升/公斤/分钟）。脂质水平没有差异性变化，因为所有受试者的高密度脂蛋白胆固醇和总胆固醇略有降低，载脂蛋白 A-I 和载脂蛋白 A-I 与载脂蛋白 B 的比率增加。然而，有氧组倾向于表现出较低水平的载脂蛋白 A-II 和较高的载脂蛋白 A-I 与载脂蛋白 A-II 比率。我们得出的结论是，绝经前和绝经后女性的有氧能力和血脂水平在运动中经历了相似的变化，并且有氧运动和非有氧运动对血脂水平的短期影响通常是可比的。
This study examined the effects of aerobic exercise on lipid levels in premenopausal and postmenopausal women. Fifty healthy middle-aged women (mean age, 50 years) were randomly assigned to 12 weeks of either aerobic exercise (walking and jogging) or nonaerobic strength exercise (circuit Nautilus training). Concentrations of total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, and very low density lipoprotein cholesterol were assessed, along with apolipoprotein (apo) A-I, apo A-II, apo B, and triglycerides. To document changes in aerobic capacity, maximum treadmill testing was performed with expired-gas analysis before and after the exercise program. Aerobic exercise was associated with an 18% improvement in peak VO2. Women in the aerobic group had an increased VO2, from 26.7 to 31.4 ml/kg/min (p less than 0.0001), while the VO2 of the women in the strength training group did not change (25.8 ml/kg/min before and after). There were no differential changes in lipid levels because all subjects experienced slight reductions in high density lipoprotein cholesterol and total cholesterol and increases in apo A-I and the apo A-I to apo B ratio. There was a tendency for the aerobic group to exhibit lower levels of apo A-II and a greater apo A-I to apo A-II ratio, however. We conclude that premenopausal and postmenopausal women experience similar changes in aerobic capacity and lipid levels with exercise and that the short-term effects of aerobic and nonaerobic exercise on lipid profiles are generally comparable.