Antenatal patterns of uterine activity in low-risk women: A longitudinal study

Antenatal patterns of uterine activity in low-risk women: A longitudinal study
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DOI:
10.1111/j.1479-828x.1997.tb02242.x
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发表时间:
1997-05-01
影响因子:
1.7
通讯作者:
Evans, SF
Evans, SF
中科院分区:
医学4区
文献类型:
--
作者:
Dickinson, JE;Godfrey, M;Evans, SF

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令人惊讶的是,关于正常产科人口子宫活动的产前模式的信息缺乏,大多数研究都集中在早产高危妇女身上。我们进行了一项前瞻性纵向研究,以调查低早产风险单胎妊娠妇女的子宫活动模式。招募了20名孕妇,在怀孕的后半段,每周两次使用动态子宫动力学仪记录她们的子宫活动。收集到的数据被传送到中央接收站进行分析。随着妊娠的进展,每小时检测到的宫缩中位数逐渐增加,在37-40周达到峰值并趋于稳定(20-24周的中位数为0次/小时,在37-40周上升到5.4次/小时)。在那些有子宫活动的妇女中,随着妊娠的进展,收缩持续时间和挠曲幅度明显增加。在整个妊娠晚期,高振幅宫缩的次数逐渐增加。胎次增加与产前子宫收缩频率增加无关。在整个妊娠期间,正常的日常体力活动和子宫收缩频率之间没有明显的联系。在正常的人类妊娠中,在整个妊娠后半期,胎儿子宫活动的频率、持续时间和幅度都有一个稳定的、渐进的增加。子宫收缩的轮廓从妊娠中期的低振幅、低频模式转变为足月时的高振幅、高频模式。
There is a surprising lack of information on antenatal patterns of uterine activity in the normal obstetric population, with the majority of research having focussed on women at high-risk for preterm birth. We conducted a prospective longitudinal study to investigate patterns of uterine activity in women with singleton gestations at low-risk for preterm birth. Twenty pregnant women were recruited and their uterine activity was recorded using ambulatory tocodynamometry twice weekly throughout the latter half of pregnancy. The collected data were transmitted to a central receiving station for analysis. As gestation advanced there was a progressive increase in the median number of contractions detected per hour, peaking and stabilizing at 37-40 weeks (median of 0 contractions/hour at 20-24 weeks rising to 5.4 contractions/hour at 37-40 weeks). In those women with uterine activity, contraction duration and amplitude of deflection significantly increased as gestation advanced. There was a progressive increase in the number of higher amplitude contractions throughout the third trimester. Increasing parity was not associated with increasing antenatal uterine contraction frequency. No association between normal daily physical activity and uterine contraction frequency was evident throughout gestation. In normal human pregnancy there is a steady, progressive increase in the frequency, duration and amplitude of antenatal uterine activity throughout the latter half of gestation, The uterine contractile profile alters from one of a low amplitude, low frequency pattern in the second trimester to a higher amplitude, higher frequency pattern at term.