The effects of orbital and dorsolateral frontal cortical ablations on ethanol self-selection and emotional behaviors in monkeys (Macaca nemestrina).
The effects of orbital and dorsolateral frontal cortical ablations on ethanol self-selection and emotional behaviors in monkeys (Macaca nemestrina).
复制标题
眼眶和背外侧额叶皮质消融对猴子（Macaca nemestrina）乙醇自我选择和情绪行为的影响。
DOI：
10.1016/0028-3932(73)90045-6
复制
发表时间：
1973
期刊：
影响因子：
2.6
通讯作者：
M. Kamback
中科院分区：
文献类型：
--
作者：
M. Kamback
对经背外侧或眶额切除的雌性小辫猴进行情绪和酒精选择的研究。背外侧消融产生了更高的酒精溶液选择，而眶额病变减少了酒精的自我选择。通过记录酒精负荷或安慰剂负荷期间的攻击或厌恶行为来测量情绪的变化。背外侧消融增加了攻击行为的发生率，而眶额消融则降低了攻击行为的发生率。酒精“负荷”增加了所有小组的攻击性。眼窝额部消融减少了反感行为的发生，但在酒精负荷条件下反感行为的数量超过了背外侧和完整受试者。
Emotionality and alcohol selection were examined in female pigtail monkeys with dorsolateral or orbitofrontal ablations. Dorsolateral ablations produced a higher selection of the alcohol solution, while orbitofrontal lesions decreased self-selection of alcohol. Changes in emotionality were measured by recording aggresive or aversive behaviors during alcohol loading or placebo loading. Dorsolateral ablations increased the incidence of aggressive behaviors, while orbitofrontal ablations decresed the incidence of aggression. Alcohol “loading” increased aggression in all groups. Orbitofrontal ablations decreased the emission of aversive behaviors although under the alcohol loading condition the number of aversive behaviors exceeded that of both dorsolateral or intact subjects.